Ignatius of Loyola, the Founder of the Society of Jesus, sent his greatest son, Francis Xavier, one of the first seven members of the Jesuit order to India in 1542. FrancisXavier a zealous “Missionary on the move” landed at Goa and traveled extensively, particularly in India along the Fishery Coasts, Marava country, Mylapore (present day Chennai) to share his faith. Thus the Indian mission of the Jesuits lies at the very origin of their Order.

He sailed to Malacca and Japan in 1549 where he spent two and a half years. In April 1552 he sailed to China via Malacca from Goa, never to return alive. He died at Sancian, a small island facing China, on the 2nd of December of the same year. Wherever he went, he plunged himself into charitable and pastoral work preaching the message of God’s love to people. He worked in India for ten years, from 1542 to 1552, it is called the Xaverian decade.

St. Xavier’s College, Simdega was established by the Jesuits of Ranchi Province on August 1, 2016 a sister college of St. Xavier’s College, Ranchi which was established on July 3, 1944. St. Xavier's College, Simdega was established to provide higher educational opportunities primarily to the Christian Tribal boys and girls of Jharkhand towards “the total and integral liberation of the human person, leading to participate in the life of God himself.” Thus, to permeate the entire higher education to form credible, creative and socially committed citizens.